Muscone


CAS No. : 541-91-3

541-91-3
Price and Availability of CAS No. : 541-91-3
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25mg $50 In-stock
50mg $80 In-stock
100mg $120 In-stock
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Cat. No. : HY-N0633
M.Wt: 238.41
Formula: C16H30O
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 541-91-3 :

Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1]. In Vitro: Muscone significantly downregulates the levels of LPS-induced inflammatory cytokines and inhibits NF-κB and NLRP3 inflammasome activation in Bone marrow-derived macrophages (BMDMs).  Muscone serves as a promising and effective drug for post-myocardial infarction (MI) treatment[1].

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