Aminopterin
CAS No. : 54-62-6
(Synonyms: 4-Aminofolic acid; APGA)
| Size | Price | Stock |
|---|---|---|
| 5mg | $35 | In-stock |
| 10mg | $49 | In-stock |
| 25mg | $88 | In-stock |
| 50mg | $123 | In-stock |
| 100mg | $172 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-14518 |
| M.Wt: | 440.41 |
| Formula: | C19H20N8O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 14.71 mg/mL (ultrasonic);H2O : 5 mg/mL (ultrasonic;adjust pH to 8 with NaOH) |
Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia[1][2].
In Vitro: The IC50 value of Aminopterin (4-Aminofolic acid) against CCRF-CEM cells during 72 h of exposure is 4.4 nM[2].
Aminopterin (4-Aminofolic acid) produces a marked inhibition of mitosis in low concentrations in human leukemic leukocytes[4].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Aminopterin
- Cat. No.:
- HY-14518
- Quantity:
Your information is safe with us.