UF010
CAS No. : 537672-41-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $35 | In-stock |
| 10mg | $50 | In-stock |
| 25mg | $90 | In-stock |
| 50mg | $140 | In-stock |
| 100mg | $220 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-18976 |
| M.Wt: | 271.15 |
| Formula: | C11H15BrN2O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
UF010 is a selective inhibitor of class I HDAC. UF010 has cytotoxicity to cancer cells and reduces neuroinflammation in the hippocampus. UF010 can be used for the research of neurological diseases[1][2][3]. In Vitro:UF010 (500 nM, 4 days) leads to a signifcant reduction in rod production with a concomitant increase in Müller cells[1]. UF010 (10-100 μM, 72 h) has cytotoxicity to B16F10 cells, MCF-7 cells, A549 cells, 4T1 cells, HEK-293 cells and HCEC cells[2]. In Vivo:UF010 (15 mg/kg, Intraperitoneal injection, single dose) contributes considerably to the inflammatory regulation of hippocampal neurons in postoperative cognitive dysfunction (POCD) mice[4]. UF010 (15 mg/kg, Intraperitoneal injection, single dose) has antitumor therapeutic efficacy in the 4T1-Luc tumor-bearing mouse model[5].
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