Clovamide
CAS No. : 53755-02-5
(Synonyms: trans-Clovamide)
| Size | Price | Stock |
|---|---|---|
| 1mg | $33 | In-stock |
| 5mg | $70 | In-stock |
| 10mg | $110 | In-stock |
| 25mg | $170 | In-stock |
| 50mg | $300 | In-stock |
| 100mg | $510 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-122267 |
| M.Wt: | 359.33 |
| Formula: | C18H17NO7 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C) |
Clovamide (trans-Clovamide), a natural phenolic compound, is a potent antioxidant. Clovamide is an excellent ROS and oxygen radical scavenger. Clovamide also has anti-inflammatory and neuroprotective effects[1][2]. Clovamide is an anti-microbial with activity against the human pathogens influenza A subtype H5N1, Trypanosoma evansi, and Heliobacter pylori[3].
In Vitro: Clovamide is able to protect neurons from injury in three in vitro models of neuronal death: oxidative stress, excitotoxicity and OGD/reoxygenation. In SH-SY5Y human neuroblastoma cells, Clovamide (10-100 µM) significantly protects cell death, with an EC50 value of 3.6 µM. Clovamide also significantly enhances PPARγ expression[2].
Clovamide inhibits growth of three pathogens of cacao in the genus Phytophthora, is a substrate for cacao polyphenol oxidase, and is a contributor to enzymatic browning. Clovamide inhibiteds proteinase and pectinase in vitro[3].
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