NKL 22
CAS No. : 537034-15-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $37 | In-stock |
| 10mg | $60 | In-stock |
| 25mg | $120 | In-stock |
| 50mg | $190 | In-stock |
| 100mg | $300 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100384 |
| M.Wt: | 325.40 |
| Formula: | C19H23N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
NKL 22 (compound 4b) is a potent and selective inhibitor of histone deacetylases (HDAC), with an IC50 of 199 and 69 nM for HDAC1 and HDAC3, respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 (IC50≥1.59 μM). NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice[1][2][3].
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