(E)-Ferulic acid


CAS No. : 537-98-4

(Synonyms: (E)-Coniferic acid)

537-98-4
Price and Availability of CAS No. : 537-98-4
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Cat. No. : HY-N0060B
M.Wt: 194.19
Formula: C10H10O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 537-98-4 :

(E)-Ferulic acid, an orally active antioxidant, induces apoptosis. (E)-Ferulic acid has anti-proliferation and anti-migration effects. (E)-Ferulic acid can reduce the hepatorenal toxicity and oxidative stress induced by Tamoxifen (HY-13757A) in rats[1][2]. IC50 & Target:β-catenin, Bcl-2 Family[1] In Vitro:(E)-Ferulic acid (0.03-0.6 mM, 24 h, 48 h) has anti-proliferation and anti-migration effects in human lung cancer cell line H1299 [1].
In Vivo:(E)-Ferulic acid (100 mg/kg, gavage, once a day for 21 days) can reduce the effect of liver and kidney toxicity and oxidative stress posed by tamoxifen in rats. [2].

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