Isoferulic acid


CAS No. : 537-73-5

(Synonyms: 3-Hydroxy-4-methoxycinnamic acid)

537-73-5
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Cat. No. : HY-N0761
M.Wt: 194.19
Formula: C10H10O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 537-73-5 :

Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes[1][2][3][4]. In Vitro:Isoferulic acid has IC50 values of 7.30, 4.58, 1.08, 8.84, 7.69, 1.57 and 13.33 μg/mL, respectively, for lipid peroxidation, DPPH and ABTS radical scavenging, reducing power on Fe3+ and Cu2+ ions, and hydroxyl and superoxide anion radical scavenging[1]. In Vivo:Isoferulic acid (0.5-10 mg/kg; intravenous injection; single dose) has an improving effect in a diabetic rat model[2].
Isoferulic acid (0.25-1.0 mg/kg; oral administration; 4 days) has antiviral activity in mice infected with the influenza virus[3].

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