N-Bis(2-hydroxypropyl)nitrosamine


CAS No. : 53609-64-6

(Synonyms: Di(2-hydroxypropyl)nitrosamine; Diisopropanolnitrosamine)

53609-64-6
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Cat. No. : HY-112085
M.Wt: 162.19
Formula: C6H14N2O3
Purity: >98 %
Solubility: DMSO : ≥ 125 mg/mL
Introduction of 53609-64-6 :

N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity. In Vitro: N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity[1]. In Vivo: N-Bis(2-hydroxypropyl)nitrosamine causes the tumors to develop in the lung, liver, and thyroid of rats at a dose of 100 ppm, in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at a dose of 500 ppm, and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at both doses[1]. Bisphenol A (BPA) enhances the susceptibility to thyroid carcinoma stimulated by N-Bis(2-hydroxypropyl)nitrosamine (DHPN; 2800 mg/kg) in rats[2].

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