Luteolin-3-O-beta-D-glucuronide
CAS No. : 53527-42-7
| Size | Price | Stock |
|---|---|---|
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| 10mg | $345 | In-stock |
| 25mg | $675 | In-stock |
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| Cat. No. : | HY-N4099 |
| M.Wt: | 462.36 |
| Formula: | C21H18O12 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Luteolin-3-O-beta-D-glucuronide, a glucuronide derivative of Luteolin (HY-N0162), is found in the leaves of Rosmarinus officinalis L. Luteolin-3-O-beta-D-glucuronide inhibits nitrite production in macrophages and binds strongly to FYN kinase[1][2].
In Vitro:Luteolin-3-O-beta-D-glucuronide binds to human FYN kinase via hydrogen bonding, van der Waals forces, and Coulomb interactions, and exhibits strong binding affinity[2].
Luteolin-3-O-beta-D-glucuronide exhibits favorable computational simulation characteristics of good solubility, synthesizability and non-toxicity, with no blood-brain barrier permeability and low intestinal absorption rate[2].
In Vivo:Luteolin-3-O-beta-D-glucuronide demonstrates low in vivo toxicity in C. elegans[2].
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