Isogosferol
CAS No. : 53319-52-1
(Synonyms: (+)-Isogospherol; Isogospherol)
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| Cat. No. : | HY-N3480 |
| M.Wt: | 286.28 |
| Formula: | C16H14O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Isogosferol ((+)-Isogospherol; Isogospherol) is a potent anti-inflammatory agent. Isogosferol decreases LPS (HY-D1056)-stimulated NO and IL-1β expression. Isogosferol decreases the LPS (HY-D1056)-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2[1].
In Vitro:Isogosferol (100, 200 µM; 1+16 h) decreases LPS (HY-D1056)-stimulated NO expression in RAW 264.7 cells[1].
Isogosferol (0, 25, 50, 100, 200 µM; 1+16 h) decreases LPS-stimulated expression of iNOS, COX-2 protein in a dose-dependent manner[1].
Isogosferol (0, 25, 50, 100, 200 µM; 1+1 h) decreases the LPS-stimulated expression of NF-κB and pERK1/2 in a dose-dependentmanner[1].
Isogosferol (50, 100, 200 µM µM; 1+16 h) decreases LPS-stimulated release of the pro-inflammatory cytokine, IL-1β[1].
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