L-NMMA (acetate)
CAS No. : 53308-83-1
(Synonyms: Tilarginine (acetate); Methylarginine (acetate))
| Size | Price | Stock |
|---|---|---|
| 1mg | $25 | In-stock |
| 5mg | $50 | In-stock |
| 10mg | $70 | In-stock |
| 25mg | $120 | In-stock |
| 50mg | $170 | In-stock |
| 100mg | $248 | In-stock |
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| Cat. No. : | HY-18732A |
| M.Wt: | 248.28 |
| Formula: | C9H20N4O4 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 50 mg/mL |
L-NMMA (Tilarginine) acetate is a non-selective and competitive inhibitor of nitric oxide synthase. L-NMMA acetate inhibits three subtypes, namely nNOS, eNOS, and iNOS, and reduces NO production. L-NMMA acetate alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA acetate is applicable to research related to nociception, bone cancer pain, and myopia[1][2][3].
In Vivo:L-NMMA (50 µg; i.t.; single administration) acetate significantly alleviates bone cancer-induced mechanical allodynia and thermal hyperalgesia in mice at 2 and 12 h post-treatment[1].
L-NMMA (20 nmol; intravitreal injection; once every other day; 2 to 4 weeks) acetate alleviates choroidal fibrosis and delays myopia progression by inhibiting the NO signaling pathway in lens-induced myopic guinea pigs[2].
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