Sitamaquine (hydrochloride)
CAS No. : 5330-29-0
(Synonyms: WR 6026 (hydrochloride))
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| Cat. No. : | HY-19688A |
| M.Wt: | 416.43 |
| Formula: | C21H35Cl2N3O |
| Purity: | >98 % |
| Solubility: |
Sitamaquine (WR6026) hydrochloride, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine hydrochloride inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine hydrochloride is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes[1][2].
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