| Size | Price | Stock |
|---|---|---|
| 1g | $12 | In-stock |
| 5g | $15 | In-stock |
| 25g | $31 | In-stock |
| 100g | $100 | In-stock |
| 500g | $357 | In-stock |
| 1 kg | Get quote | |
| 2 kg | Get quote | |
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| Cat. No. : | HY-N7076 |
| M.Wt: | 304.42 |
| Formula: | C16H32O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Aleuritic acid ((±)-erythro-Aleuritic acid; α-Aleuritic acid) is a polyhydroxy fatty acid found in plant cutin and shellac. Aleuritic acid disrupts the Mycobacterium tuberculosis Nei2-β-clamp (DnaN) interaction and binds to the Mycobacterium tuberculosis β-clamp without affecting the intrinsic DNA glycosylase activity of Nei2. Aleuritic acid self-assembles with pectin to form cutin body nanoparticles. Aleuritic acid is the major component of Croton crassifolius. Aleuritic acid is used in mycobacterial and fragrance-related research[1][2][3].
In Vitro:Aleuritic acid (50-800 µM; 30 min) inhibits the interaction between Mycobacterium tuberculosis Nei2 and the β clamp with an IC50 of 71.49 µM, without affecting the intrinsic glycosylase activity of MtbNei2[2].
Aleuritic acid binds to the Mycobacterium tuberculosis β-clamp with a KD of 27 nM[2].
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