CV1808
CAS No. : 53296-10-9
(Synonyms: 2-Phenylaminoadenosine)
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| Cat. No. : | HY-103183 |
| M.Wt: | 358.35 |
| Formula: | C16H18N6O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with Kis of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively[1].
In Vitro: CV1808 demonstrates an inhibitory effect on anti-IgE-induced activation at 100 μM[1].
In the presence of Forskolin (1 μM in PC12 cells; 10 μM in Jurkat cells) the EC50 value for CV1808 is 2 μM[2].
In Vivo: Single afferent arterioles of Sprague-Dawley rats are visualized and superfused with solutions containing CV1808 (CV-1808). Superfusion with CV1808 (0.002-2 μM) dilates afferent arterioles[3].
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