2"-O-Galloylhyperin
CAS No. : 53209-27-1
| Size | Price | Stock |
|---|---|---|
| 1mg | $61 | In-stock |
| 5mg | $130 | In-stock |
| 10mg | $210 | In-stock |
| 25mg | $400 | In-stock |
| 50mg | $585 | In-stock |
| 100mg | $824 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-N0526 |
| M.Wt: | 616.48 |
| Formula: | C28H24O16 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
2''-O-Galloylhyperin is an active natural compound with anti‑inflammatory, antioxidant, anti‑adipogenic, antifibrotic, and cytostatic activities. 2''-O-Galloylhyperin upregulates SIRT1/Nrf2 signaling, inhibits NF-κB and MAPK (ERK1/2, p38, JNK) phosphorylation, suppresses TSHR activation, reduces ROS accumulation, and enhances SOD and GSH-Px activities. 2''-O-Galloylhyperin protects against LPS-induced tissue injury, enhances survival, and inhibits adipogenesis and fibrosis. 2"-O-Galloylhyperin can be used for the research of sepsis, acute lung injury, and thyroid eye disease[1][2][3][4]. In Vivo:2"-O-Galloylhyperin (10-50 mg/kg; i.p.; single dose; 1 hour prior to LPS challenge) attenuates LPS-induced acute lung injury in male ICR mice in a dose-dependent manner[2].
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