Acemetacin


CAS No. : 53164-05-9

(Synonyms: TVX 1322)

53164-05-9
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5g $98 In-stock
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Cat. No. : HY-B0482
M.Wt: 415.82
Formula: C21H18ClNO6
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic);H2O : < 0.1 mg/mL
Introduction of 53164-05-9 :

Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor. IC50 & Target: COX[1]. In Vitro: Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. Acemetacin (TVX 1322), a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of Acemetacin (TVX 1322) is that it reduces gastric damage when compared to indometacin. From Wikipedia.

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