Rapamycin (Standard)
CAS No. : 53123-88-9
(Synonyms: Sirolimus (Standard); AY-22989 (Standard); NSC 226080 (Standard))
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| Cat. No. : | HY-10219R |
| M.Wt: | 914.17 |
| Formula: | C51H79NO13 |
| Purity: | >98 % |
| Solubility: |
Rapamycin (Standard) is the analytical standard of Rapamycin (HY-10219). This product is intended for research and analytical applications. Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[1]. Rapamycin is an autophagy activator, an immunosuppressant[2]. IC50 & Target:IC50: 0.1 nM (mTOR)[1]
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