3,6-Diaminoacridine (dihydrochloride)
CAS No. : 531-73-7
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| Cat. No. : | HY-B1741A |
| M.Wt: | 282.17 |
| Formula: | C13H13Cl2N3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO;10 mM in DMSO |
Proflavine dihydrochloride is a multifunctional acridine compound. 3,6-Diaminoacridine dihydrochloride is an acridine dye and also a DNA inserter. Proflavine dihydrochloride is a potent broad-spectrum antibacterial agent, and its mechanism is to insert into bacterial DNA, interfering with replication and transcription, causing bacterial lysis. 3,6-Diaminoacridine dihydrochloride is a Kir3.2 potassium channel blocker and can be used to study the neurological phenotype of Down syndrome. 3,6-Diaminoacridine dihydrochloride can penetrate the stratum corneum of the skin and accumulate in the cell nucleus and long-term exposure may induce skin cancer or other malignant tumors[1][2][3].
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