Androsin
CAS No. : 531-28-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $240 | In-stock |
| 25mg | $432 | In-stock |
| 50mg | $690 | In-stock |
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| Cat. No. : | HY-N1399 |
| M.Wt: | 328.31 |
| Formula: | C15H20O8 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Androsin is an active compound isolated from Picrorhiza Kurroa Royle ex Benth. Androsin activates AMPKα/PI3K/Beclin1/LC3 signaling pathway, inhibits SREBP1c/FASN signaling pathway. Androsin can be used in research of asthma and non-alcoholic fatty liver disease (NAFLD). Androsin is orally active[1][2].
In Vitro:Androsin (0.001-0.1 mg/mL) inhibited the histamine release in human polymorphonuclear leukocytes induced by allergens (such as a-IgE)[1].
In Vivo:Androsin (10 mg/kg, po, single dose) prevents allergen (Ovalbumin) or platelet-activating factor (PAF)-induced bronchial obstruction in guinea pigs[1].
Androsin (10 mg/kg, po, once daily for 7 weeks) induces autophagy and inhibits lipid accumulation, alleviates the symptoms of non-alcoholic fatty liver disease (NAFLD) in HFrD-fed ApoE-/- mouse models[2].
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