Isoetharine
CAS No. : 530-08-5
(Synonyms: Isoetarine)
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| Cat. No. : | HY-B1481A |
| M.Wt: | 239.31 |
| Formula: | C13H21NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Isoetharine (Isoetarine) is an orally active selective agonist of β-adrenergic receptors. Isoetharine is a catechol-like drug and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2]. In Vitro: Isoetharine (50 μM, 18 hours) can induce the production and release of [35S]sulfated metabolites of catecholic drugs in HepG2 human hepatoma cells[1]. In Vivo: Isoetharine inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model[2].
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