Prednisone


CAS No. : 53-03-2

(Synonyms: Dehydrocortisone)

53-03-2
Price and Availability of CAS No. : 53-03-2
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500mg $25 In-stock
1g $40 In-stock
5g $155 In-stock
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Cat. No. : HY-B0214
M.Wt: 358.43
Formula: C21H26O5
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 53-03-2 :

Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus[1][2]. In Vivo:Prednisone (intramuscular injection, 10 mg/kg once a day, on days 4 to 13) reduces the survival rate on days lower than the control group in BALB/c mice with encephalomyocarditis virus myocarditis. Besides, myocardial virus titers reaches a maximum on day 4, but there is no antibody titer, and on day 8 virus titers remains elevated and antibody titers is also high. On day 10, antibody titers are significantly lower than controls, while viral titers remains significantly elevated[2].
Prednisone (5 mg/kg, intragastrically administration, daily) can cause changes in FA metabolism in SLE mouse (MRL/lpr) model[3].

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