Nanaomycin A
CAS No. : 52934-83-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $450 | In-stock |
| 10mg | $720 | In-stock |
| 25mg | $1440 | In-stock |
| 50mg | $2400 | In-stock |
| 100mg | $3840 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-103397 |
| M.Wt: | 302.28 |
| Formula: | C16H14O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Nanaomycin A is the first selective DNMT3B inhibitor with an IC50 of 500 nM. Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells[1]. Nanaomycin A inhibits in vitro growth of the human malaria parasite Plasmodium falciparum with an IC80 value of 33.1 nM[2].
In Vitro: Nanaomycin A (10-10000 nM; 72 hours) has a distinct cytotoxic effect in all three cell lines[1].
Nanaomycin A (0.5, 5 μM; 72 hours) reveals induction of RASSF1A protein expression in A549 cells[1].
Nanaomycin A (5 μM; 72 hours) has an 18-fold relative induction[1].
Nanaomycin A not affects the enzymatic activity of DNMT1[1].
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