Nanaomycin A


CAS No. : 52934-83-5

52934-83-5
Price and Availability of CAS No. : 52934-83-5
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Cat. No. : HY-103397
M.Wt: 302.28
Formula: C16H14O6
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 52934-83-5 :

Nanaomycin A is a selective DNMT3B inhibitor with an IC50 of 500 nM. Nanaomycin A inhibits the in vitro growth of human Plasmodium falciparum with an IC80 of 33.1 nM[1][2]. In Vitro:Nanaomycin A (10-10000 nM; 72 hours) exhibited significant cytotoxicity in all three cell lines[1].
Nanaomycin A (0.5-5 μM; 72 hours) induced RASSF1A protein expression in A549 cells[1].
Nanaomycin A is a selective inhibitor of DNMT3B that induces genome demethylation and does not affect the enzyme activity of DNMT1[1].

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