Pyridoxamine 5′-phosphate

Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate^[1]. In Vitro: Pyridoxamine 5′-phosphate can be transformed from pyridoxal 5′-phosphate. Purified His-tagged omega-TA CV2025 from Chromobacterium violaceum is capable of complete conversion of pyridoxal 5′-phosphate to pyridoxamine 5′-phosphate in the presence of (S)-α-methylbenzylamine (MBA) as the amine donor.