Scutellarein
CAS No. : 529-53-3
(Synonyms: 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone)
| Size | Price | Stock |
|---|---|---|
| 2mg | $45 | In-stock |
| 5mg | $64 | In-stock |
| 10mg | $90 | In-stock |
| 25mg | $145 | In-stock |
| 50mg | $215 | In-stock |
| 100mg | $320 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-N0752 |
| M.Wt: | 286.24 |
| Formula: | C15H10O6 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 30 mg/mL |
Scutellarein is a natural flavonoid compound with anti-inflammatory effects.
In Vitro:Scutellarein (0-200 μM, 24 h) inhibits NO production, reduces the mRNA expression levels of iNOS and TNF-α in LPS-activated RAW264.7 cells[1].
Scutellarein (0-50 μM, 24 h) inhibits proliferation, migration, colony formation and induces the apoptosis of HT1080 cells[3].
Scutellarein (0-50 μM, 24 h) inhibits MMP-2, -9 and -14 expression and NF-κB activation in HT1080 cells[3].
Scutellarein shows DPPH, ABTS+·, ·OH radical-scavenging activity (IC50: 16.84 μM, 3.00 μM, 0.31 mM respectively)[4].
In Vivo:Scutellarein (50 mg/kg, in diet, 16 weeks) shows anti-obesity effects, and shows lipid lowering and liver protective effects in HFD mice[2].
Scutellarein (50 and 500 mg/kg) inhibits tumor growth in a mouse HT108 xenograft model[3].
Scutellarein (0-1.40 mmol/kg, p.o.) improves neuronal injury, and protects rats from cerebral ischemia[5].
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