| Size | Price | Stock |
|---|---|---|
| 100mg | $66 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-B1218 |
| M.Wt: | 314.36 |
| Formula: | C15H14N4O2S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion[1][2][3]. In Vitro:Sulfaphenazole (10 μM; for 1 h) causes the numbers of light-induced apoptotic and necrotic cells decreased by 33 and 44%, respectively[1]. In Vivo:Sulfaphenazole (5.13 mg/kg; intraperitoneal injections; daily; for 8 weeks) restores endothelium-mediated relaxation in diabetic mice[2].
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