Eudesmin
CAS No. : 526-06-7
(Synonyms: (-)-Eudesmin; Eudesmine; (-)-Eudesmine)
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| 5mg | $430 | In-stock |
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| Cat. No. : | HY-N2357 |
| M.Wt: | 386.44 |
| Formula: | C22H26O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities[1]. IC50 & Target: S6K1[1] In Vitro: Treatment of mesenchymal stem cells (MSCs) with Eudesmin (20, 40, and 80μM) disturbs adipogenesis via suppression of S6K1 signaling pathway. Eudesmin treatment inhibits activation and nuclear translocation of S6K1. S6K1-mediated phosphorylation of H2B at serine 36 (H2BS36p) is reduced upon Eudesmin treatment[1].
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