| Size | Price | Stock |
|---|---|---|
| 1mg | $393 | Get quote |
| 5mg | $805 | Get quote |
| 10mg | $1190 | Get quote |
| 25mg | $1905 | Get quote |
| 50mg | $2574 | Get quote |
| 100mg | $3465 | Get quote |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-N3085 |
| M.Wt: | 518.51 |
| Formula: | C26H30O11 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Phellamurin is a plant flavonone glycoside from the leaves of Phellodendron amurense and inhibits intestinal P-glycoprotein. Phellamurin also inhibits egg laying by Papilio protenor. Phellamurin induces cells apoptosis and has anti-tumor activity[1][2][3].
In Vitro: Phellamurin (0-10?μg/mL; 48 hours; U2OS and Saos-2?cells) treatment leads to a repression of cell viability in U2OS and Saos-2?cells in a dose-dependent manner[1].
Phellamurin (0-10?μg/mL; 48 hours; U2OS and Saos-2?cells) treatment concentration-dependently promots the apoptosis of U2OS and Saos-2?cells[1].
Phellamurin (0-10?μg/mL; 48 hours; U2OS and Saos-2?cells) treatment declines the ratios of p-PI3K/PI3K, p-AKT/AKT, and p-mTOR/mTOR in U2OS and Saos-2?cells[1].
In Vivo: Phellamurin (50?mg/kg/day; intraperitoneal injection; daily; for 21 days; female BALB/c nude mice) treatment represses osteosarcoma tumor growth in vivo. The ratios of p-PI3K/PI3K, p-AKT/AKT, and p-mTOR/mTOR are decreased in xenograft in Phellamurin-treated mice[1].
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