3b-Hydroxy-5-cholenoic acid


CAS No. : 5255-17-4

5255-17-4
Price and Availability of CAS No. : 5255-17-4
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1g $280 In-stock
5g $975 In-stock
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Cat. No. : HY-113315
M.Wt: 374.56
Formula: C24H38O3
Purity: >98 %
Solubility: Ethanol : 4 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 5255-17-4 :

3β-Hydroxy-5-cholenoic acid is a steroidal monohydroxy bile acid and serves as a substrate for sulfation reactions. It is applicable to the research of extrahepatic biliary atresia and recurrent intrahepatic cholestasis of pregnancy[1][2]. In Vitro: 3b-Hydroxy-5-cholenoic acid (compound 15) (up to 10 μM; 24 h) does not act as a pharmacological chaperone for NPC1L1L1072T/L1168I in HEK293 cells, with no observed correction of the mutant protein's ER localization defect at concentrations up to 10 μM for 24 h[1].

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