| Size | Price | Stock |
|---|---|---|
| 5mg | $200 | In-stock |
| 10mg | $300 | In-stock |
| 25mg | $515 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-N2592 |
| M.Wt: | 358.39 |
| Formula: | C20H22O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (ultrasonic) |
Isobutylshikonin is a kind of shikonin pigments found in hairy root culture of Lithospermum canescens. Isobutylshikonin decreases cell viability induces marked changes in JA-4 cells with nuclear condensation and swelling in the presence of LPS (HY-D1056)[1]. In Vitro:
Isobutylshikonin (0-20 μM, 4 h) decreases cell viability of JA-4 cells in the presence of LPS (HY-D1056) (100ng/mL) but alone has no effect on macrophage viability[1].
Isobutylshikonin (5 μM, 4 h) induces marked changes in JA-4 cells with nuclear condensation and swelling in the presence of LPS (100ng/mL), but alone does not cause morphological changes of the macrophages[1].
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