Isobutylshikonin


CAS No. : 52438-12-7

52438-12-7
Price and Availability of CAS No. : 52438-12-7
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5mg $200 In-stock
10mg $300 In-stock
25mg $515 In-stock
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Cat. No. : HY-N2592
M.Wt: 358.39
Formula: C20H22O6
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic)
Introduction of 52438-12-7 :

Isobutylshikonin is a kind of shikonin pigments found in hairy root culture of Lithospermum canescens. Isobutylshikonin decreases cell viability induces marked changes in JA-4 cells with nuclear condensation and swelling in the presence of LPS (HY-D1056)[1]. In Vitro:

Isobutylshikonin (0-20 μM, 4 h) decreases cell viability of JA-4 cells in the presence of LPS (HY-D1056) (100ng/mL) but alone has no effect on macrophage viability[1].

Isobutylshikonin (5 μM, 4 h) induces marked changes in JA-4 cells with nuclear condensation and swelling in the presence of LPS (100ng/mL), but alone does not cause morphological changes of the macrophages[1].

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