Malic enzyme inhibitor ME1


CAS No. : 522649-59-8

(Synonyms: ME1)

522649-59-8
Price and Availability of CAS No. : 522649-59-8
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1mg $84 In-stock
5mg $255 In-stock
10mg $440 In-stock
25mg $880 In-stock
50mg $1500 In-stock
100mg $2550 In-stock
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Cat. No. : HY-124861
M.Wt: 351.40
Formula: C20H21N3O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 522649-59-8 :

Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM[1][2]. IC50 & Target: IC50: 0.15 μM (Malic enzyme)[1] In Vitro: Malic enzyme inhibitor ME1 (ME1; ME1*) (50 μM; 72 hours) shows a significant reduction in total cell numbers[2].
Malic enzyme inhibitor ME1 shows a significant reduction in cell viability/metabolic activity in MTS cell[2].
Malic enzyme inhibitor ME1 dose-dependently reduces the number of colonies formed by both HCT116 and HT29 cells[2].

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