Lumisterol 3 (>90%)
CAS No. : 5226-01-7
(Synonyms: 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C)
| Size | Price | Stock |
|---|---|---|
| 1mg | $195 | In-stock |
| 5mg | $720 | In-stock |
| 10mg | $1250 | In-stock |
| 25mg | $2550 | In-stock |
| 50mg | $4200 | In-stock |
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| Cat. No. : | HY-112023 |
| M.Wt: | 384.64 |
| Formula: | C27H44O |
| Purity: | >98 % |
| Solubility: | DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C) |
Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D[1].
In Vitro: Lumisterol 3 (L3) (1-100 nM, 24 h) significantly reduces UVB-induced cellular oxidant formation in a dose-dependent manner and inhibits the proliferation of UVB-irradiated keratinocytes[2].
Lumisterol 3 (L3) (100 nM, 24 h) promotes repair of cellular DNA damage induced by UVB irradiation and increases the nuclear/cytosolic Nrf2 ratio and nuclear p53 expression level in UVB-irradiated cells[2].
Lumisterol 3 (L3) (100 nM, 3 h) significantly enhances the expression levels of Nrf2-regulated antioxidant proteins, including catalase and HO-1 in UVB-irradiated cells[2].
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