Dequalinium (Chloride)
CAS No. : 522-51-0
| Size | Price | Stock |
|---|---|---|
| 10mg | $30 | In-stock |
| 25mg | $50 | In-stock |
| 50mg | $72 | In-stock |
| 100mg | $90 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-B0567 |
| M.Wt: | 527.57 |
| Formula: | C30H40Cl2N4 |
| Purity: | >98 % |
| Solubility: | DMSO : < 1 mg/mL;H2O : 0.99 mg/mL (ultrasonic;warming;adjust pH to 3 with 1 M HCL;heat to 60°C) |
Dequalinium chloride is an Apamin (HY-P0256)-sensitive potassium channel selective blocker. Dequalinium chloride is a cationic, lipophilic mitochondrial poison. Dequalinium chloride is also an antagonist pf α7 nAChR, and an anti-microbial antiseptic agent with a broad bactericidal and fungicidal activity[1][2][3][4].
In Vitro: Dequalinium chloride blocks angiotensin II (100 nM)-evoked K+ loss in guinea-pig hepatocytes, with an IC50 of 1.5 μM[5].
Dequalinium (0-100 μg/mL, 72 h) chloride inhibits cell growth in human Pca cell lines (PC3, DU145, LNCaP, MDA-PCA-2B), and induces cell apoptosis in PC3 cells (0.9 μM, 4 h)[7].
In Vivo: Dequalinium chloride shows a LD50 of 18.3 mg/kg in mice (i.p., a single time)[2].
Dequalinium chloride (2 mg/kg, i.p., daily for 10 days) inhibits the tumor growth of mouse bladder carcinoma MB49[3].
Dequalinium chloride (2 mg/kg, s.c.) reduces Diisopropylfluorophosphate-induced tremors (organophosphate poisoning) in mice[6].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Dequalinium (Chloride)
- Cat. No.:
- HY-B0567
- Quantity:
Your information is safe with us.