Thio-TEPA
CAS No. : 52-24-4
| Size | Price | Stock |
|---|---|---|
| 25mg | $90 | In-stock |
| 50mg | $140 | In-stock |
| 100mg | $230 | In-stock |
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| Cat. No. : | HY-17574 |
| M.Wt: | 189.22 |
| Formula: | C6H12N3PS |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL;H2O : ≥ mg/mL |
Thio-TEPA is a DNA alkylating agent, with antitumor activity. IC50 & Target: DNA Alkylator[1] In Vitro: Thio-TEPA exhibits alkylating activity in rat liver slice incubation. Thio-TEPA does not affect the viability of rat liver slices, and is not accumulated in the slices at all doses of 2, 5, 10 mM[1]. In Vivo: Thio-TEPA (20 mg/kg, i.p.) with total body irradiation (TBI) enhances donor-type blood chimerism during the first 10 weeks but is not dramatically higher than that of TBI group alone. Thio-TEPA alone improves both short- and long-term engraftment in mice[2].
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