ATP (disodium trihydrate)
CAS No. : 51963-61-2
(Synonyms: Adenosine-5'-triphosphate (disodium trihydrate))
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| 500g | $240 | In-stock |
| 1000g | $408 | In-stock |
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| Cat. No. : | HY-B2176A |
| M.Wt: | 605.19 |
| Formula: | C10H20N5Na2O16P3 |
| Purity: | >98 % |
| Solubility: | DMSO : 1 mg/mL (ultrasonic;warming;heat to 80°C);H2O : 175 mg/mL (ultrasonic) |
ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation[1][2].
In Vitro: ATP disodium trihydrate (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs[3].
ATP disodium trihydrate (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner[4].
ATP disodium trihydrate promotes neutrophil chemotaxis in vitro[4].
In Vivo: ATP disodium trihydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo[4].
ATP disodium trihydrate induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo[4].
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