SP4206
CAS No. : 515846-21-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $600 | In-stock |
| 5mg | $1250 | In-stock |
| 10mg | $1880 | In-stock |
| 25mg | $3550 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-119424 |
| M.Wt: | 662.56 |
| Formula: | C30H37Cl2N7O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
SP4206 is an IL-2/IL-2Rα interaction inhibitor. SP4206 binds with high affinity (Kd=70 nM) to IL-2 and blocks binding to its natural receptor IL-2Rα (Kd=10 nM)[1]. IC50 & Target: IL-2/IL-2Rα interaction[1] In Vitro: SP4206 binds the WT IL-2, IL-2 variant K35L/M39V, IL-2 variant P65A, and IL-2 variant V69A with EC50s of 68.8, 80.1, 117.0, and 10.4 nM, respectively[1].
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