Sulfathiourea
CAS No. : 515-49-1
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| Cat. No. : | HY-100010 |
| M.Wt: | 231.29 |
| Formula: | C7H9N3O2S2 |
| Purity: | >98 % |
| Solubility: |
Sulfathiourea is an inhibitor of Pneumocystis carinii dihydropteroate synthetase (dihydropteroate synthetase), with an IC50 of 0.022 μM and a Ki of 16.5 nM. Sulfathiourea blocks folate biosynthesis by inhibiting the enzyme that links 7,8-dihydro-6-hydroxymethylpterin pyrophosphate with p-aminobenzoic acid to form dihydropteroate. Sulfathiourea can be used in research related to *Pneumocystis carinii* pneumonia[1]. In Vitro:Sulfathiourea potently inhibits recombinant *Pneumocystis carinii* dihydropteroate synthase, with an IC50 of 22 nM and a Ki of 16.5 nM[1].
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