Carbazochrome (sodium sulfonate)
CAS No. : 51460-26-5
(Synonyms: AC-17)
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| 50mg | $75 | In-stock |
| 100mg | $120 | In-stock |
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| Cat. No. : | HY-B0491A |
| M.Wt: | 322.27 |
| Formula: | C10H11N4NaO5S |
| Purity: | >98 % |
| Solubility: | H2O : 6.67 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : ≥ 49 mg/mL |
Carbazochrome sodium sulfonate (AC-17) is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome sodium sulfonate is an antihemorrhagic agent[1]. In Vitro: Carbazochrome (0.1-10 µM) inhibits the Bradykinin induced and thrombin-induced formation of [3H]IP3 in a concentration-dependent manner[1]. Carbazochrome (0.1-1 µM), when included from 30 min before stimulation, significantly suppressed the enhancement of permeability induced by vasoactive substances[1]. In Vivo: Carbazochrome inhibits the severe pulmonary dysfunction induced by the intravenous injection of radiographic contrast media. Carbazochrome (1-10 mg/kg, i.v.) attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats[2].
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