Rubropunctamine
CAS No. : 514-66-9
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| Cat. No. : | HY-N6643 |
| M.Wt: | 353.41 |
| Formula: | C21H23NO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Rubropunctamine is a redMonascus pigment. Not only Rubropunctamine exerts antibiotic action against bacteria but also against some yeast and filamentous fungi strains. Rubropunctamine has potential embryotoxicity and teratogenicity[1].
In Vitro: Rubropunctamine (0.32-32 nM; 48 h) inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), with an IC50 of 433 mol ratio/32 pmol TPA[2].
Rubropunctamine (1 h) exhibits moderate scavenging activity (inhibitory ratio (IR)=1.5) against NO generation by (±)-(E)-methyl-2[(E)-hydroxy-imino]-5-nitro-6-methoxy-3-hexemide (NOR 1) in normal human hepato cells[2].
In Vivo: Rubropunctamine inhibits TPA-induced inflammation in mice, with an ID50 of 0.32 mg/ear[2].
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