Taraxerone
CAS No. : 514-07-8
| Size | Price | Stock |
|---|---|---|
| 1mg | $180 | In-stock |
| 5mg | $540 | In-stock |
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| Cat. No. : | HY-N1177 |
| M.Wt: | 424.70 |
| Formula: | C30H48O |
| Purity: | >98 % |
| Solubility: | THF : 10 mg/mL (ultrasonic);DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) |
Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1]. IC50 & Target:EC50: 512.42 μM (ADH); 500.16 μM (ALDH)[1] In Vivo: Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1]. Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].
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