Substance P (7-11)
CAS No. : 51165-05-0
| Size | Price | Stock |
|---|---|---|
| 2mg | $50 | In-stock |
| 5mg | $80 | In-stock |
| 10mg | $140 | In-stock |
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| Cat. No. : | HY-P1492 |
| M.Wt: | 612.78 |
| Formula: | C31H44N6O5S |
| Purity: | >98 % |
| Solubility: | H2O : 1.96 mg/mL (ultrasonic;adjust pH to 2 with HCl) |
Substance P (7-11) is a C-terminal fragment of Substance P which can cause an increase in the intracellular calcium concentration. In Vitro: Substance P (7-11) increases PGE2 and collagenase production at concentrations greater than 1 μM. Substance P (7-11), but not intact SP, SP-(1-4), SP-(1-6), SP- (8-11) or SP-(9-1 1), nor the tachykinins NKA and NKB, causes an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. The maximal change in intracellular calcium induced by 10 μM Substance P (7-11) was 140±30 nM[1].
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