9-Hydroxyellipticin
CAS No. : 51131-85-2
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| Cat. No. : | HY-101775 |
| M.Wt: | 262.31 |
| Formula: | C17H14N2O |
| Purity: | >98 % |
| Solubility: |
9-hydroxyellipticine is an inhibitor of Topo II and RyR, exhibiting high affinity for DNA with a Pka value of 9.8 at pH 7.4. It has antitumor, antioxidant, and catecholamine-releasing activities, with IC50 values of 1.6 μM and 1.2 μM for Hela S-3 and 293T cells, respectively. It also demonstrates anticancer effects in L1210 leukemia mice[1].
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