ATC0065
CAS No. : 510732-84-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $251 | In-stock |
| 10mg | $400 | In-stock |
| 25mg | $800 | In-stock |
| 50mg | $1200 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-107626 |
| M.Wt: | 625.35 |
| Formula: | C25H31BrCl2F3N5O |
| Purity: | >98 % |
| Solubility: |
ATC0065 is a potent, selective and orally active melanin-concentrating hormone (MCH) receptor 1 (MCHR1) antagonist with an IC50 of 15.7 nM for human MCHR1. ATC0065 does not exhibits significant activity for MCHR2. ATC0065 has anxiolytic and antidepressant activities[1].
In Vitro:ATC0065 also exhibits high to moderate affinity for 5-HT2B and 5-HT1A receptors with IC50 values of 266 nM and 62.9 nM, reapectively.
In Vivo:ATC0065 (3-30 mg/kg; oral administration; 3 h prior to the test) shows antidepressant-like effects in rats[1].
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