Acipimox
CAS No. : 51037-30-0
(Synonyms: K-9321)
| Size | Price | Stock |
|---|---|---|
| 5g | $50 | In-stock |
| 10g | $74 | In-stock |
| 25g | $179 | In-stock |
| 100g | $523 | In-stock |
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| Cat. No. : | HY-B0283 |
| M.Wt: | 154.13 |
| Formula: | C6H6N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : 20 mg/mL (ultrasonic) |
Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity[1][2][3].
In Vitro: Acipimox (0-100 µM; 0-4 hours) enhances leptin release from adipocytes isolated from Sprague-Dawley rats in a time- and dose- dependent manner[2].
Acipimox (10 mM) stimulats leptin release in adipocytes from Streptozotocin (STZ)-treated and Zucker diabetic fat (ZDF) rats[2].
In Vivo: Acipimox (50 mg/kg; i.p.) significantly lowers circulating free fatty acid (FFA) and glucose in high-fat fed mice[3].
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