Salbutamol (hemisulfate)
CAS No. : 51022-70-9
(Synonyms: Albuterol (hemisulfate); AH-3365 (hemisulfate))
| Size | Price | Stock |
|---|---|---|
| 100mg | $50 | In-stock |
| 500mg | $120 | In-stock |
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| Cat. No. : | HY-B0436 |
| M.Wt: | 288.14 |
| Formula: | C13H22NO5S0.5 |
| Purity: | >98 % |
| Solubility: | DMSO : 2 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
Salbutamol (Albuterol) hemisulfate is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol hemisulfate promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol hemisulfate can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease[1][2].
In Vitro:Salbutamol (16 μM; 24 h) hemisulfate significantly induces EMT, migration and invasion by ERK (extracellular signal-regulated kinase) phosphorylation in gastric cancer cells[1].
In Vivo:Salbutamol (5 mg/kg; oral administration; 2 weeks) hemisulfate can increase tumor growth in nude mice with gastric cancer[1].
Salbutamol (6 mg/kg; oral administration; 4 weeks) hemisulfate has a significant protective effect against Streptozotocin (HY-13753)-induced skeletal muscle atrophy in diabetic rats[2].
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