Amcinonide
CAS No. : 51022-69-6
(Synonyms: CL-34699)
| Size | Price | Stock |
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| Cat. No. : | HY-B1197 |
| M.Wt: | 502.57 |
| Formula: | C28H35FO7 |
| Purity: | >98 % |
| Solubility: |
Amcinonide is an inhibitor of NO release (IC50 = 3.38 nM). Amcinonide inhibits NNC-induced expression of the proinflammatory genes iNOS, TNF-α, and IL-1β in glial cells. Amcinonide reduces the numbers of T6+/Ia+ cells with a concomitant increase in T6+/Ia- cells. Amcinonide induces a selective reduction in expression of Ia antigens. Amcinonide can also be studied in research for eczematous dermatitis[1][2][3]. In Vitro:Amcinonide (Compound 95745) (0-1000 nM, 48 h) significantly inhibits the production of NO (IC50 = 3.38 nM) in EOC13 cells [1].
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