Tiapride (hydrochloride)
CAS No. : 51012-33-0
| Size | Price | Stock |
|---|---|---|
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| Cat. No. : | HY-B1196 |
| M.Wt: | 364.89 |
| Formula: | C15H25ClN2O4S |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 200 mg/mL;DMSO : 31.25 mg/mL (ultrasonic) |
Tiapride hydrochloride is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent[1][2]. In Vivo:Tiapride hydrochloride (10-200 mg/kg, ip) antagonizes ethanol-induced hyperactivity in mouse models, without affecting the sleep time[2].
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