Echinocystic acid
CAS No. : 510-30-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $30 | In-stock |
| 10mg | $45 | In-stock |
| 25mg | $85 | In-stock |
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| Cat. No. : | HY-N0271 |
| M.Wt: | 472.70 |
| Formula: | C30H48O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Echinocystic acid is a natural pentacyclic triterpene with potent antioxidant, anti-inflammatory and analgesic activities[1][2].
In Vitro:Echinocystic acid (2.5-10 μM; pretreated 1 h) inhibits IL-1β-induced NF-κB and MAPK activation[1].
Echinocystic acid suppresses IL-1β-induced MMP-13, NO, and PGE2 production in a dose-dependent manner. IL-1β up-regulated the expression of COX-2 and iNOS, and the increase is inhibited by Echinocystic acid[1].
In Vivo:Echinocystic acid (5 mg/kg intragastrically daily for 5 days) shows anti-depression activities in the mouse model of reserpine-induced pain-depression dyad[2].
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