Atropine
CAS No. : 51-55-8
(Synonyms: Tropine tropate; DL-Hyoscyamine)
| Size | Price | Stock |
|---|---|---|
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| 500mg | $100 | In-stock |
| 1g | $130 | In-stock |
| 5g | $210 | In-stock |
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| Cat. No. : | HY-B1205 |
| M.Wt: | 289.38 |
| Formula: | C17H23NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 96.6 mg/mL;H2O : 2.9 mg/mL (ultrasonic;warming) |
Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia[1][2][3][4]. IC50 & Target:IC50: 0.39 nM (Human mAChR M4) and 0.71 nM (Chicken mAChR M4)[3] In Vitro:Atropine (Tropine tropate; 1 μM; pulmonary veins and arteries) inhibits ACh-induced relaxations in human pulmonary veins[4]. In Vivo:Atropine (Tropine tropate; 10 mg/kg; i.p.; once, for 40 minutes; Peromyscus sp.) inhibits the cardiac arrhythmia which normally occurs throughout torpor[2].
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