7ACC1
CAS No. : 50995-74-9
(Synonyms: DEAC; Coumarin D 1421; D 1421)
| Size | Price | Stock |
|---|---|---|
| 250mg | $9 | In-stock |
| 1g | $12 | In-stock |
| 5g | $21 | In-stock |
| 10g | $41 | In-stock |
| 25g | $76 | In-stock |
| 100g | $266 | In-stock |
| 200 g | Get quote | |
| 500 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-D0067 |
| M.Wt: | 261.28 |
| Formula: | C14H15NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic) |
7ACC1 (DEAC; Coumarin D 1421; D 1421) is a monocarboxylate transporter 1 (MCT-1)/MCT-4 specifc blocker. 7ACC1 attenuates renal cancer cell proliferation, migration, invasion and down-regulates the levels of MCT1/MCT4 expression and extracellular lactate. 7ACC1 is promising for research of cancers[1][2][3].
In Vitro:7ACC1 (10 μM, 0-96 h) attenuates the viability, decreases cell migration and invasion in co-culturing conditions of 786-O cells and HUVECs[1].
7ACC1 (10 μM, 24 h) inhibits the protein expressions of MCT1 and MCT4, down-regulates the extracellular lactate levels in co-culturing conditions of 786-O cells and HUVECs[1].
7ACC1 (0-1 μM, 24 h) inhibit the influx but not the efflux of lactate in cancer cells[2].
In Vivo:7ACC1 (3 mg/kg, i.p., daily for 12 days) inhibits the growth of MCT-expressing cervix SiHa, colorectal HCT116 and breast MCF-7 tumors in mice[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- 7ACC1
- Cat. No.:
- HY-D0067
- Quantity:
Your information is safe with us.