Ankaflavin
CAS No. : 50980-32-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $61 | In-stock |
| 5mg | $286 | In-stock |
| 10mg | $542 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-N6642 |
| M.Wt: | 386.48 |
| Formula: | C23H30O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Ankaflavin, isolated from Monascus-Fermented red rice, is an orally active PPARγ agonist. Ankaflavin exhibits selective cytotoxic effect and induces cell death through apoptosis on cancer cells. Ankaflavin has anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects[1][2].
IC50 & Target:PPARγ[2].
In Vitro: Ankaflavin (0-50 µg/mL, 48 h) shows cytotoxicity against cancer cells with no significant toxicity toward normal cells[1].
Ankaflavin (0-30 µg/mL, 0-48 h) arrests Hep G2 cell cycle at sub-G1 phase in a dose- and time-dependent manner[1].
Ankaflavin (25 µg/mL, 48 h) induces Hep G2 cell apoptosis[1].
In Vivo: Ankaflavin (10 mg/kg; p.o.; daily for 28 days) shows antidiabetic and anti-inflammatory activity, improves liver function and pancreatic function[2].
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